{"id":39623,"date":"2021-03-31T12:12:48","date_gmt":"2021-03-31T10:12:48","guid":{"rendered":"https:\/\/dev.yuveo.eu\/lexikon\/is-conservative-treatment-possible-for-dupuytrens-disease\/"},"modified":"2025-08-25T15:38:31","modified_gmt":"2025-08-25T13:38:31","slug":"is-conservative-treatment-possible-for-dupuytrens-disease","status":"publish","type":"encyclopedia","link":"https:\/\/www.yuveo.de\/en\/lexikon\/is-conservative-treatment-possible-for-dupuytrens-disease\/","title":{"rendered":"Is conservative treatment possible for Dupuytren&#8217;s disease?"},"content":{"rendered":"<div class=\"et_pb_column et_pb_column_1_3 et_pb_column_12 et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_module et_pb_code et_pb_code_3\">\n<div class=\"et_pb_code_inner\">\n<figure id=\"attachment_26994\" aria-describedby=\"caption-attachment-26994\" style=\"width: 247px\" class=\"wp-caption alignright\"><img fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-26994 size-medium\" src=\"https:\/\/www.yuveo.de\/wp-content\/uploads\/2021\/03\/dupuytren-erkrankung-grad-3-10192w-247x300.jpg\" alt=\"Dupuytren's, grade 3\" width=\"247\" height=\"300\" srcset=\"https:\/\/www.yuveo.de\/wp-content\/uploads\/2021\/03\/dupuytren-erkrankung-grad-3-10192w-247x300.jpg 247w, https:\/\/www.yuveo.de\/wp-content\/uploads\/2021\/03\/dupuytren-erkrankung-grad-3-10192w.jpg 411w\" sizes=\"(max-width: 247px) 100vw, 247px\" \/><figcaption id=\"caption-attachment-26994\" class=\"wp-caption-text\">Dupuytren&#8217;s disease, grade 3<\/figcaption><\/figure>\n<p>Many attempts have already been made to get <a href=\"https:\/\/www.yuveo.de\/en\/hand\/dupuytrens\/\">Dupuytren&#8217;s disease<\/a> under control by means of <strong>conservative treatment<\/strong>, <strong>unfortunately without any real success.<\/strong><\/p>\n<\/div>\n<\/div>\n<\/div>\n<ul class=\"list\">\n<li>Pharmacodynamic exheresis &#8211; Only short-term partial successes were achieved with an <strong>injection of<\/strong> a mixture of hyaluronidase and trypsin (Hueston 1974, Lamb 1981).<\/li>\n<li><strong>Colleague nose treatment<\/strong> &#8211; The relapse rate after 2 years is 25 % (Mc Carthy 1992). Enzymatic tendon ruptures and nerve damage can be caused. <\/li>\n<li><strong>Allopurinol<\/strong> &#8211; improvement in joint extension by approx. 8\u00b0 according to Murrel (1987). A greater improvement was only observed in individual cases. <\/li>\n<\/ul>\n<p>To date, there is <strong>no<\/strong> scientific evidence for the effectiveness of the following conservative treatment measures: corticoid injections, cryotherapy, laser therapy, shock wave therapy.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Many attempts have already been made to get Dupuytren&#8217;s disease under control by means of conservative treatment, unfortunately without any real success. Pharmacodynamic exheresis &#8211; Only short-term partial successes were achieved with an injection of a mixture of hyaluronidase and trypsin (Hueston 1974, Lamb 1981). Colleague nose treatment &#8211; The relapse rate after 2 years [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"template":"","encyclopedia-tag":[147,249,125],"class_list":["post-39623","encyclopedia","type-encyclopedia","status-publish","hentry","encyclopedia-tag-dupuytren","encyclopedia-tag-erkrankung-der-hand","encyclopedia-tag-hand"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.yuveo.de\/en\/wp-json\/wp\/v2\/encyclopedia\/39623","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.yuveo.de\/en\/wp-json\/wp\/v2\/encyclopedia"}],"about":[{"href":"https:\/\/www.yuveo.de\/en\/wp-json\/wp\/v2\/types\/encyclopedia"}],"author":[{"embeddable":true,"href":"https:\/\/www.yuveo.de\/en\/wp-json\/wp\/v2\/users\/1"}],"wp:attachment":[{"href":"https:\/\/www.yuveo.de\/en\/wp-json\/wp\/v2\/media?parent=39623"}],"wp:term":[{"taxonomy":"encyclopedia-tag","embeddable":true,"href":"https:\/\/www.yuveo.de\/en\/wp-json\/wp\/v2\/encyclopedia-tag?post=39623"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}